CASE STUDY

Diabetes Drug Effectiveness

Context:

One of the clients has launched a new oral medication for Type 2 Diabetes. The HEOR team wants to compare its real-world effectiveness against existing therapies using claims and EHR data.

Resolution:

Our team identified patients with Type 2 Diabetes initiating therapy which was compared to HbA1c reduction at 6 months between new drug vs. standard therapy and then assessed adherence (Proportion of Days Covered, PDC). Finally, they summarize safety outcomes (hypoglycaemia events).

Result:

The outcome analysis resulted as HbA1c reduction wherein paired t-test or mixed model was finalised. The Adherence showed PDC ≥ 80% threshold and in terms of frequency of hypoglycaemia ICD codes was analysed under safety.

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    Recent Case-studies

    Diabetes Drug Effectiveness

    Context:

    One of the clients has launched a new oral medication for Type 2 Diabetes. The HEOR team wants to compare its real-world effectiveness against existing therapies using claims and EHR data.

    Resolution:

    Our team identified patients with Type 2 Diabetes initiating therapy which was compared to HbA1c reduction at 6 months between new drug vs. standard therapy and then assessed adherence (Proportion of Days Covered, PDC). Finally, they summarize safety outcomes (hypoglycaemia events).

    Result:

    The outcome analysis resulted as HbA1c reduction wherein paired t-test or mixed model was finalised. The Adherence showed PDC ≥ 80% threshold and in terms of frequency of hypoglycaemia ICD codes was analysed under safety.

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